Neutral Theory, Transposable Elements, and Eukaryotic Genome Evolution

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Transposable elements and host genome evolution.

Several recent reports have challenged the idea that transposable elements (TEs) are mainly 'selfish' or 'junk' DNA with little importance for host evolution. It has been proposed that TEs have the potential to provide host genomes with the ability to enhance their own evolution. They might also be a major source of genetic diversity, allowing response to environmental changes. Because the rela...

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Transposable elements and the evolution of eukaryotic genomes.

W hen transposable elements (TEs) were discovered in maize by Barbara McClintock 50 years ago they were regarded as a curiosity; now they are known to be the most abundant component of probably all eukaryotic genomes. They account for almost 50% of the human genome and 70% of the genomes of some grass species, including maize. As such, they make up the vast majority of the output of genome sequ...

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Transposable elements and the evolution of eukaryotic complexity.

Eukaryotic transposable elements are ubiquitous and widespread mobile genetic entities. These elements often make up a substantial fraction of the host genomes in which they reside. For example, approximately 1/2 of the human genome was recently shown to consist of transposable element sequences. There is a growing body of evidence that demonstrates that transposable elements have been major pl...

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Perspective : Transposable Elements , Parasitic Dna , and Genome

The nature of the role played by mobile elements in host genome evolution is reassessed considering numerous recent developments in many areas of biology. It is argued that easy popular appellations such as ‘‘selfish DNA’’ and ‘‘junk DNA’’ may be either inaccurate or misleading and that a more enlightened view of the transposable element-host relationship encompasses a continuum from extreme pa...

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Evolution and consequences of transposable elements.

Recent studies on transposable elements (TEs) have shed light on the mechanisms that have shaped their evolution. In addition to accumulating nucleotide substitutions over evolutionary time, TEs appear to be especially prone to genetic rearrangements and vertical transmissions across even distantly related species. As a consequence of replicating in host genomes, TEs have a significant mutation...

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ژورنال

عنوان ژورنال: Molecular Biology and Evolution

سال: 2018

ISSN: 0737-4038,1537-1719

DOI: 10.1093/molbev/msy083